The Macedonian Donor Registry Foundation (MKDR) was established on 03.02.2002 as part of the ICGEB project (CRP/MAC03-01) “AMBIGUITIES RESOLUTION OF HLA GENOTYPES IN MACEDONIAN POPULATION”. On July 30, 2018, the Macedonian Donor Registry Foundation (MKDR) expanded its activities and changed its name to the Scientific Foundation SPIROSKI.

Most of the work of the foundation is publishing scientific journals, the most famous and extensive of which is the scientific journal Open Access Macedonian Journal of Medical Sciences. Following the name change, activities began for establishing a nongovernmental Marrow Donor Registry (in addition to the existing state Bone Marrow Donor Registry of the IIBHG) as an additional potential for treating patients with blood cancer with marrow transplantations.